Mechanisms and disease consequences of nonalcoholic

Nonalcoholic fatty liver disease (NAFLD) is emerging as the leading chronic liver disease worldwide (Loomba and al, 2013; Younossi et al., 2016).NAFLD is viewed as the hepatic manifestation of metabolic syndrome and is commonly associated with metabolic risk factors, including obesity, dyslipidemia, hypertension, and diabetes (Chalasani et al., 2018; …

Experimental study on the development mode and evolution mechanism …

Experimental study on the development mode and evolution mechanism of sodium silicate solidified sand under different temperatures and curing paths ... sodium hydroxide and water. River sand near Chengdu City, Sichuan Province, was used for this study. ... The theoretical maximum strength growth rate can be derived from the first-order ...

A state-dependent multi-mechanism model for sands

A state-dependent multi-mechanism model for sands in three-dimensional space is proposed within the framework of critical-state soil mechanics. The mechanical deformation behaviour of sands is characterised with a macroscopic volumetric mechanism and a number of one-dimensional equivalent microscopic shear mechanisms (EMSMs) in various orientations. …

DNA modification mechanisms and gene activity during development

DNA modification mechanisms and gene activity during development. DNA modification mechanisms and gene activity during development Science. 1975 Jan 24;187(4173):226-32. Authors R Holliday, J E Pugh. PMID: 1111098 No …

Research on sand control effect and micro-plugging mechanism of sand

Research on sand control effect and micro-plugging mechanism of sand control medium in the development of natural gas hydrate reservoir. Author links open overlay panel Jiping Ding a b ... The research results are conducive to understanding mechanisms of sand control elements plugged by gravel during the exploitation of hydrate reservoirs and ...

(PDF) Effects of rock types and crushing mechanism on the 3D

This study aims to investigate the effect of rock types, i.e., granite, conglomerate rock, limestone, and crushing mechanism, i.e., Vertical Shaft Impact (VSI) crusher, Horizontal Shaft Impact ...

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Photodynamic therapy

Photodynamic therapy - mechanisms, photosensitizers and combinations Biomed Pharmacother. 2018 Oct:106:1098-1107. doi: 10.1016/j.biopha.2018.07.049. ... Over the last decade, a significant acceleration in the development of nanotechnology has been observed. The combination of photosensitizers with nanomaterials can improve the photodynamic ...

Study on liquefaction mechanism of saturated sand considering …

The soil in actual site is anisotropic consolidated with an initial consolidation ratio k c =σ 10 /σ 30 and a deviator stress (σ 10 −σ 30), where σ 10 and σ 30 denote the initial vertical effective stress and the initial confining pressure, respectively. The effect of consolidation ratio on the liquefaction resistance of sand has been studied using laboratory tests over the decades.

(PDF) Soil Liquefaction: Mechanism and Assessment …

The basic mechanisms of earthquake-induced soil liquefaction are introduced by considering the shaking of a block on a thin granular layer, which mechanical behaviour is modelled with a ...

Bacterial persisters: molecular mechanisms and therapeutic development

Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing) bacteria that survive in stress environments such as antibiotic exposure, acidic and starvation conditions.

Micromechanical investigation of the aging mechanism in sand

Initially, the aging of sand was speculated to be caused by the precipitation of carbonate or silica gel that leads to cementation at particle contacts (Mitchell and Solymar, 1984).Baxter and Mitchell (2004) examined this mechanism for two sands aged under 100 kPa vertical pressure in rigid wall cells at different relative densities and temperatures.

Chemical sand stabilization: A review of material, mechanism, …

Chemical sand stabilization has potential for desertification control and this method is characterized by its speed and convenience in operation compared with other stabilization technologies.

Quantitative Analysis of Mechanisms for Water-Related Sand …

Based on the time frame of sand production record, four major possible chemical reactions between reservoir sand and formation water are identified and analyzed, including …

Sand Control: Sand Characterization, Failure Mechanisms, and …

Mechanisms for sand failure include: tensile, shear, cohesive, and pore collapse. Additionally, failure due to chemical effects can occur when the cementation materials are …

Mechanism and modeling of infiltration of saturated sand by …

The slurry pressure-balance shield tunneling method is commonly used to excavate water-bearing strata, particularly saturated sand layers, owing to its high safety and effective pressure control (Bezuijen et al., 2006, Liang et al., 2020, Liu et al., 2020).Slurry primarily consisting of bentonite (a nonmetallic, montmorillonite-rich mineral) is selected because of its …

Recrystallization mechanisms and microstructure development in …

Recrystallization nucleation mechanisms were subject of contention for several years. It is now appreciated that the recrystallization nucleation mechanism differs from that characteristic of conventional phase transformations where classical nucleation theories are applicable [13].The nuclei which give rise to new recrystallized grains are believed to be …

Sand Production Management for Unconsolidated …

complete sand control and limited sand production. This book presents a comprehensive introduction of technologies applied in the development of poorly consolidated sandstone reservoirs. The contents include studies of sand production mechanisms, sand production prediction and productivity index appraisal, selection of well completion approaches,

Molecular mechanisms of aging and anti-aging strategies

Aging is a complex and multifaceted process involving a variety of interrelated molecular mechanisms and cellular systems. Phenotypically, the biological aging process is accompanied by a gradual loss of cellular function and the systemic deterioration of multiple tissues, resulting in susceptibility to aging-related diseases. Emerging evidence suggests that …

Mechanism of Compaction Grouting in Sand and Efficiency …

In this paper, using the Nor-sand model, an finite difference method (FDM) simulation was carried out to study the grout efficiency and grout pressure of compaction …

Particle gradation effects on creep characteristics and the …

With the rapid development of marine engineering, calcareous sand as a primary material for island construction in the world, has become the foundation for large-scale projects and infrastructure [1], [2], [3]prehending the creep behavior of calcareous sand is crucial for guaranteeing the long-term stability of engineering facilities in land reclamation and island …

Increasing soil carbon storage: mechanisms, effects of agricultural

The international 4 per 1000 initiative aims at supporting states and non-governmental stakeholders in their efforts towards a better management of soil carbon (C) stocks. These stocks depend on soil C inputs and outputs. They are the result of fine spatial scale interconnected mechanisms, which stabilise/destabilise organic matter-borne C. Since 2016, the CarboSMS …

Development of dynamic centrifuge models for measurement and

Representative range of ASRs observed in the texture-optimization process: (a) loose Ottawa sand seeded with dyed black sand; (b) dense Ottawa sand seeded with blue dyed sand. Standard deviation of subset pixel intensities, σ Is, and the sum of squares of subset pixel intensity gradients (SSSIG) for example subsets (48 × 48 pixels) of chosen ...

Microscopic mechanical analysis of sand production using a new

A new discrete element method and computational fluid dynamics coupling model is developed by combining the resolved and unresolved method. To overcome the inaccuracy of fluid-particle drag force calculation and limitation on the size ratio of fine particles to fluid meshes, two aspects of improvements are made for sand production simulation over the existing …

Property For Sale in Vanderbijlpark CE

Private Property has 212 houses, apartments, complexes, farms, land for sale in Vanderbijlpark CE. View photos, virtual tours and detailed property descriptions.

Constructed wetland substrates: A review on development, …

Substrates are used to construct the body of CWs, which play a central role in treatment process (Mlih et al., 2020).The effects of substrates (physical filtration and interception, adsorption and ion exchanges), plants and microorganisms on pollution treatment are simultaneously present in CWs (Drayer and Richter, 2016; Fu et al., 2018).The categories and …

Development of pore water pressure in anisotropically consolidated sand

The development of pore water pressure plays a vital role in the evaluation of liquefaction resistance of sand. Sand in situ is typically anisotropically consolidated due to gravitational deposition and external loading. However, the influence of anisotropic consolidation stress state on the development of pore water pressure in sand has not been adequately …

Thermal evolution of chemical structure and mechanism of oil sands

Notably, the physico–chemical properties of oil sands depend to a large extent on their origin and geological environment in which they were deposited. Therefore, Indonesian oil sands differ from Canadian oil sands as no water film exists between bitumen and minerals of Indonesian oil sands and they belong to oil-wet type oil sands [6, 7 ...

Mechanisms of NAFLD development and therapeutic strategies

Mechanisms of NAFLD development and therapeutic strategies Nat Med. 2018 Jul;24(7):908-922. doi: 10.1038/s41591-018-0104-9. Epub 2018 Jul 2. Authors Scott L Friedman 1, Brent A Neuschwander-Tetri 2, Mary Rinella 3, Arun J al 4 Affiliations 1 …

Cold stress tolerance mechanisms in plants. A review

The human population is increasing at an alarming rate, whereas at the same time agricultural productivity is decreasing due to the effect of various environmental problems. In particular, cold stress is a serious threat to the sustainability of crop yields. Indeed, cold stress can lead to major crop losses. Various phenotypic symptoms in response to cold stress include poor germination ...